Why You’ll Love It

Jarrow Formulas® SAM-e 400 provides a full 400 mg SAM-e (net yield) from 800 mg of SAM-e tosylate disulfate. SAM-e 400 is manufactured under low temperature and low humidity and is enteric-coated to ensure a biologically active product.

SKU: 790011200208

About This Brand

Jarrow Formulas

With so many supplement brands on the market, choosing what makes the cut for your wellness ritual can be a little overwhelming. The key is finding those that go above and beyond basic formulations to assure you get the most from your daily dose of vitamins and minerals. Jarrow Formulas is one such brand. For over 40 years, the premium supplement line has expertly crafted an extensive line of...
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Other Ingredients: cellulose, glyceryl behenate, magnesium stearate (vegetable source), silicon dioxide, mannitol, sodium starch glycolate, and an enteric coating(methacrylate copolymers, magnesium silicate, titanium dioxide, triethyl citrate, silicon dioxide and riboflavin)

Disclaimer: Information, statements, and reviews regarding products have not been evaluated by the Food and Drug Administration. Results vary person to person, and there is no guarantee of specific results. Thrive Market assumes no liability for inaccuracies or misstatements about products.


Nutrition information

Serving Size:
1 tablet
Servings Per
Amount per serving
% daily value
S-Adenosyl Methionine
400 mg
(from 800 mg of SAM-e tosylate disulfate)
† Daily Value Not Established

Keep out of the reach of children. WARNING: Individuals using prescribed medications such as antidepressants, including Selective Serotonin Re-Uptake Inhibitors (SSRIs) and MAO Inhibitors should consult a physician before using. Individuals with Parkinson’s disease, bi-polar disorder or manic depression should not use SAM-e. Do not use if pregnant or nursing. Do not exceed recommended intake. May cause gastrointestinal upset in some persons. If you experience discomfort, discontinue use. No wheat, no gluten, no soybeans, no dairy, no egg, no fish/shellfish, no peanuts/tree nuts.

11 Members have left reviews!


Posted   by Denise from Rancho Cordova, California
Verified Purchase
Love this brand of supplements
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Posted   by David from Columbia City, Indiana
Verified Purchase
Feel a lot better
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A good choice for uplifting mood

Posted   by Lisa from HOLLAND, Michigan
Verified Purchase
My husband tried this after I read about it in a medical article. A doctor of holistic medicine said this does help people in his practice. It did indeed help a lot and after going off in the spring he wanted to continue so we will be re-ordering on a regular basis.
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Posted   by Keri from Pittsburgh, Pennsylvania
Verified Purchase
Good product
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horse pills

Posted   by Lorrie from MARSHFIELD, Massachusetts
Verified Purchase
I wanted the 400 instead of 200 but wasn't expecting such huge pills. I have a hard time swallowing pills so this was not a good choice for me.
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Helps with mood

Posted   by Sarah from BIG SKY, Montana
Verified Purchase
I have had great luck with SAM-e, helps improve my mood and joint pain with no side effects. I may use it for lif now, and the cost here is decent.
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Essential supplement

Posted   by George from THOUSAND OAKS, California
Verified Purchase
Wow, does this stuff work like crazy. Currently not in the budget for every day, but when I do use the stuff consistently, I can certainly tell the difference in my mood. That said, this is the best price you’ll find it out there!
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great product

Posted   by Deidra from CENTER LINE, Michigan
Verified Purchase
I used to buy this supplement for my dog. He had an early form of Cushing's (I believe), and the doctor said that Sam-E would help.
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Cannot do without this❣️

Posted   by Deborah from OAK PARK, California
Verified Purchase
I heard about this supplement from Suzanne Somers years ago...... I’ve been taking it since.....Thrive makes it much more affordable.. I love the monthly shipment... it’s so convenient and I know I’ll never run out.
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Such a great deal

Posted   by MS from DALLAS, Texas
Verified Purchase
Such a great deal - SAM-E is a daily must for me, and thrive saves me so much money on it. Really helps my mood, appetite, stability and overall mental well being.
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(Displaying 10 of 11 reviews)